ABSTRACT
Objective To study the feasibility and value of magnetic resonance diffusion tensor imaging (DTI) to monitor non?arteritic anterior ischemic optic neuropathy (NAION). Methods Thirty eight NAION patients (56 eyes) were divided into acute period in 17 eyes, progressive period in 16 eyes and chronic period in 23 eyes at the base of onset time. According to matching principle, 56 eyes in 38 normal controls (NCs) were enrolled. All the patients and NCs underwent MR and DTI scan. The raw data were processed by two experienced radiologists, mean diffusivity (MD), axial diffusivities (λ//), radial diffusivities (λ┴), fractional anisotropy (FA) and Length value were got. The independent sample t test was used for the parameter values between the NAION group and the NCs group. A single factor variance analysis was used to compare the parameters among different stages of NAION group. Results Compared to the NCs group, the values of FA and Length in NAION group were reduced [0.20±0.11 vs 0.31±0.12, (5.85±0.92) vs (65.11± 6.89) mm], and the differences were statistically significant (t=-4.28,-5.25;P<0.05). The values of MD andλ┴were increased [(0.16±0.04)×10-3 vs (0.10±0.04)×10-3 mm2/s, (0.16±0.05)×10-3 vs (0.09±0.03)×10-3 mm2/s] in NAION group and the differences were statistically significant (t=6.83, 7.10;P<0.05). The value of FA and Length in acute period, progressive period and chronic period of the NAION group decreased differently compared to the NCs group. At the same time, the value of MD value and λ┴in the three periods of the NAION group increased compared to the NCs groupand the differences were statistically significant (P<0.05). The value of FA between the acute period, the progressive period, and the chronic period of NAION group were statistically signficant (F=10.88, P<0.05). However, no significant differences were found in the values of MD, λ┴and Length of the NAION group (F=0.23, 0.64, 0.33, 1.38;P=0.79, 0.54, 0.72, 0.27). Conclusion The parameters of DTI can be used to monitor the damage of optic nerve and development in NAION.
ABSTRACT
Objective To evaluate the diagnostic value of CT by analyzing CT features of right-sided colon cancer.Methods CT findings of 35 cases with surgically proved right-sided colon cancer were analyzed retrospectively with regard to their pathologic features.Results 34 of 35(97.1%) were diagnosed accurately by CT . Of them , 29 cases (82.9%)were polypoid colon cancer , 6 cases were infiltrative colon cancer, 2 cases with typical “target sign”. 9 cases(25.7%) were found with pericolic infiltration during operation, 7 of 9 (77.8%) were detected by CT scan . Distal ileal involvement of 3 cases ( 8.6% ) were all detected by CT . Lymphadenopathy was showed in 11 (31.4%), 7 of 11(63.6%)were found by CT.Conclusion CT scan plays important role in diagnosis of right-sided colon cancer as well as in finding pericolic infiltration, distal ileal involvement and lymphadenopathy.